

If you use a Mac, you need to have Outlook for Mac and the latest version of Chrome, Firefox, Safari, Internet Explorer 11, or Microsoft Edge. One of the following must be set as the default browser: Internet Explorer 11 or later, the latest version of Microsoft Edge, Chrome, Firefox, or Safari.

To take advantage of Office Add-ins on Windows desktops, you must have Outlook 2013 or Outlook 2016, and Internet Explorer 11 or later must be installed (but doesn’t have to be the default browser). The server requirements for using Office Add-ins are Exchange 2013, Exchange 2016, or Exchange Online. Outlook Add-ins can display contextual information next to the Outlook item you’re viewing or composing. Office provides the ability to extend Office clients such as Word, Excel, and Outlook using web technologies like HTML, CSS, and JavaScript. We can’t talk about Dynamics 365 App for Outlook without mentioning Office Add-ins. Please note that if you use Dynamics 365 (on-premises), you need to authenticate with IFD authentication.
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Starting with the December 2016 update of Dynamics 365, you will be able to use the app if you connect Dynamics 365 (on premises) with Exchange Online, or Dynamics 365 (online) with Exchange server (on-premises). The first major improvement is hybrid support.

This blog post describes supported clients for different app features in the context of Office Add-ins. The Fall 2016 release of Dynamics 365 App for Outlook includes many significant changes.
